The global DNA synthesis market was surpassed at USD 260.7 million in 2021 and is expected to hit around USD 513.80 million by 2030, growing at a CAGR of 7.83% from 2022 to 2030.
DNA replication is the natural process of DNA synthesis. However, in the laboratory DNA is produced using genetic engineering and enzyme chemistry, artificially. This deoxyribonucleotide are used in genetic engineering, diagnostics, therapeutic applications, academic, and industrial use. Cost per base pair, error rates, lengths, and throughput, are some of the basic parameters that confirm the quality of synthesis from different companies.
Therapeutic application is continuously witnessing research and development for antibody discovery, immunology, cancer therapy, infectious disease, vaccines, and synthetic biology. The commercial growth of oligonucleotide therapeutics including miRNA inhibitors, siRNA, and oligos is supporting the growth of this segment. In comparison to traditional therapies, DNA synthesis therapeutic drugs have several potential and economic advantages. For instance, in September 2021, India gave emergency approval to Zydus Cadila’s ZyCoV-D, the first DNA vaccine, a highly stable, and cost-effective vaccine. Thus, the marketspace offers a lucrative opportunity for growth.
The application segment has been mainly categorized as:
Scope of The Report
| Report Coverage | Details |
| Market Size in 2021 | USD 260.7 million |
| Revenue Forecast by 2030 | USD 513.80 million |
| Growth rate from 2022 to 2030 | CAGR of 7.83% |
| Base Year | 2021 |
| Forecast Period | 2022 to 2030 |
| Segmentation | Service Type, Application, End User, Region |
| Companies Covered |
Thermo Fisher Scientific, Inc., Twist Bioscience, Bioneer Corporation, Eton Bioscience, LGC Biosearch Technologie, IBA GmbH, Eurofins Scientific, Integrated DNA Technologies, Inc., Quintara Biosciences, GenScript Biotech Corporation, and others |
Furthermore, the human genome project is offering several advantages in technological processes for production and reduces the time of production. This enables the synthesis of the required sequence in the required time of high throughput custom nucleotides, accelerating the market growth. In addition, the commercial success of the multi-billion dollar PCR industry and Next-generation sequencing is boosting the market growth.
Startups’ entry into the DNA synthesis market is providing improved procedures for synthesis and innovations in the medical field. For instance, as of September 2022, U.S.-based startupSiolta Therapeutics’ STMC-103H, is in phase 2 clinical investigation. Biologic drug STMC-103H has been investigated for Atopic Dermatitis and Type 1 hypersensitivity, catering to new opportunities for market growth.
Key market players are continuously upgrading manufacturing technologies to obtain high throughput and cost-controlled synthesis. In 2017, Illumina announced an investment of USD 82 million in Twist biosciences to support the development of new technology for silicon-based deoxyribonucleotides synthesis. These players are undertaking various strategic initiatives on branding, market penetration, mergers & collaborations, expansion of manufacturing facilities, and geographical expansion.
Key Players
Market Segmentation
By Service Type
By Application
By End User
By Region
Chapter 1. Introduction
1.1. Research Objective
1.2. Scope of the Study
1.3. Definition
Chapter 2. Research Methodology
2.1. Research Approach
2.2. Data Sources
2.3. Assumptions & Limitations
Chapter 3. Executive Summary
3.1. Market Snapshot
Chapter 4. Market Variables and Scope
4.1. Introduction
4.2. Market Classification and Scope
4.3. Industry Value Chain Analysis
4.3.1. Raw Material Procurement Analysis
4.3.2. Sales and Distribution Channel Analysis
4.3.3. Downstream Buyer Analysis
Chapter 5. COVID 19 Impact on DNA Synthesis Market
5.1. COVID-19 Landscape: DNA Synthesis Industry Impact
5.2. COVID 19 - Impact Assessment for the Industry
5.3. COVID 19 Impact: Global Major Government Policy
5.4. Market Trends and Opportunities in the COVID-19 Landscape
Chapter 6. Market Dynamics Analysis and Trends
6.1. Market Dynamics
6.1.1. Market Drivers
6.1.2. Market Restraints
6.1.3. Market Opportunities
6.2. Porter’s Five Forces Analysis
6.2.1. Bargaining power of suppliers
6.2.2. Bargaining power of buyers
6.2.3. Threat of substitute
6.2.4. Threat of new entrants
6.2.5. Degree of competition
Chapter 7. Competitive Landscape
7.1.1. Company Market Share/Positioning Analysis
7.1.2. Key Strategies Adopted by Players
7.1.3. Vendor Landscape
7.1.3.1. List of Suppliers
7.1.3.2. List of Buyers
Chapter 8. Global DNA Synthesis Market, By Service Type
8.1. DNA Synthesis Market, by Service Type, 2022-2030
8.1.1 Oligonucleotide Synthesis
8.1.1.1. Market Revenue and Forecast (2017-2030)
8.1.2. Universal Oligonucleotide Synthesis
8.1.2.1. Market Revenue and Forecast (2017-2030)
8.1.3. Custom Oligonucleotide Synthesis
8.1.3.1. Market Revenue and Forecast (2017-2030)
8.1.4. Gene Synthesis
8.1.4.1. Market Revenue and Forecast (2017-2030)
8.1.5. Custom Gene Synthesis
8.1.5.1. Market Revenue and Forecast (2017-2030)
8.1.6. Gene Library Synthesis
8.1.6.1. Market Revenue and Forecast (2017-2030)
Chapter 9. Global DNA Synthesis Market, By Application
9.1. DNA Synthesis Market, by Application, 2022-2030
9.1.1. Research and Development
9.1.1.1. Market Revenue and Forecast (2017-2030)
9.1.2. Academic
9.1.2.1. Market Revenue and Forecast (2017-2030)
9.1.3. Industrial
9.1.3.1. Market Revenue and Forecast (2017-2030)
9.1.4. Diagnosis
9.1.4.1. Market Revenue and Forecast (2017-2030)
9.1.5. Therapeutics
9.1.5.1. Market Revenue and Forecast (2017-2030)
Chapter 10. Global DNA Synthesis Market, By End User
10.1. DNA Synthesis Market, by End User, 2022-2030
10.1.1. Biopharmaceutical Companies
10.1.1.1. Market Revenue and Forecast (2017-2030)
10.1.2. Academic and Research Institutes
10.1.2.1. Market Revenue and Forecast (2017-2030)
10.1.3. Contract Research Organizations
10.1.3.1. Market Revenue and Forecast (2017-2030)
Chapter 11. Global DNA Synthesis Market, Regional Estimates and Trend Forecast
11.1. North America
11.1.1. Market Revenue and Forecast, by Service Type (2017-2030)
11.1.2. Market Revenue and Forecast, by Application (2017-2030)
11.1.3. Market Revenue and Forecast, by End User (2017-2030)
11.1.4. U.S.
11.1.4.1. Market Revenue and Forecast, by Service Type (2017-2030)
11.1.4.2. Market Revenue and Forecast, by Application (2017-2030)
11.1.4.3. Market Revenue and Forecast, by End User (2017-2030)
11.1.5. Rest of North America
11.1.5.1. Market Revenue and Forecast, by Service Type (2017-2030)
11.1.5.2. Market Revenue and Forecast, by Application (2017-2030)
11.1.5.3. Market Revenue and Forecast, by End User (2017-2030)
11.2. Europe
11.2.1. Market Revenue and Forecast, by Service Type (2017-2030)
11.2.2. Market Revenue and Forecast, by Application (2017-2030)
11.2.3. Market Revenue and Forecast, by End User (2017-2030)
11.2.4. UK
11.2.4.1. Market Revenue and Forecast, by Service Type (2017-2030)
11.2.4.2. Market Revenue and Forecast, by Application (2017-2030)
11.2.4.3. Market Revenue and Forecast, by End User (2017-2030)
11.2.5. Germany
11.2.5.1. Market Revenue and Forecast, by Service Type (2017-2030)
11.2.5.2. Market Revenue and Forecast, by Application (2017-2030)
11.2.5.3. Market Revenue and Forecast, by End User (2017-2030)
11.2.6. France
11.2.6.1. Market Revenue and Forecast, by Service Type (2017-2030)
11.2.6.2. Market Revenue and Forecast, by Application (2017-2030)
11.2.6.3. Market Revenue and Forecast, by End User (2017-2030)
11.2.7. Rest of Europe
11.2.7.1. Market Revenue and Forecast, by Service Type (2017-2030)
11.2.7.2. Market Revenue and Forecast, by Application (2017-2030)
11.2.7.3. Market Revenue and Forecast, by End User (2017-2030)
11.3. APAC
11.3.1. Market Revenue and Forecast, by Service Type (2017-2030)
11.3.2. Market Revenue and Forecast, by Application (2017-2030)
11.3.3. Market Revenue and Forecast, by End User (2017-2030)
11.3.4. India
11.3.4.1. Market Revenue and Forecast, by Service Type (2017-2030)
11.3.4.2. Market Revenue and Forecast, by Application (2017-2030)
11.3.4.3. Market Revenue and Forecast, by End User (2017-2030)
11.3.5. China
11.3.5.1. Market Revenue and Forecast, by Service Type (2017-2030)
11.3.5.2. Market Revenue and Forecast, by Application (2017-2030)
11.3.5.3. Market Revenue and Forecast, by End User (2017-2030)
11.3.6. Japan
11.3.6.1. Market Revenue and Forecast, by Service Type (2017-2030)
11.3.6.2. Market Revenue and Forecast, by Application (2017-2030)
11.3.6.3. Market Revenue and Forecast, by End User (2017-2030)
11.3.7. Rest of APAC
11.3.7.1. Market Revenue and Forecast, by Service Type (2017-2030)
11.3.7.2. Market Revenue and Forecast, by Application (2017-2030)
11.3.7.3. Market Revenue and Forecast, by End User (2017-2030)
11.4. MEA
11.4.1. Market Revenue and Forecast, by Service Type (2017-2030)
11.4.2. Market Revenue and Forecast, by Application (2017-2030)
11.4.3. Market Revenue and Forecast, by End User (2017-2030)
11.4.4. GCC
11.4.4.1. Market Revenue and Forecast, by Service Type (2017-2030)
11.4.4.2. Market Revenue and Forecast, by Application (2017-2030)
11.4.4.3. Market Revenue and Forecast, by End User (2017-2030)
11.4.5. North Africa
11.4.5.1. Market Revenue and Forecast, by Service Type (2017-2030)
11.4.5.2. Market Revenue and Forecast, by Application (2017-2030)
11.4.5.3. Market Revenue and Forecast, by End User (2017-2030)
11.4.6. South Africa
11.4.6.1. Market Revenue and Forecast, by Service Type (2017-2030)
11.4.6.2. Market Revenue and Forecast, by Application (2017-2030)
11.4.6.3. Market Revenue and Forecast, by End User (2017-2030)
11.4.7. Rest of MEA
11.4.7.1. Market Revenue and Forecast, by Service Type (2017-2030)
11.4.7.2. Market Revenue and Forecast, by Application (2017-2030)
11.4.7.3. Market Revenue and Forecast, by End User (2017-2030)
11.5. Latin America
11.5.1. Market Revenue and Forecast, by Service Type (2017-2030)
11.5.2. Market Revenue and Forecast, by Application (2017-2030)
11.5.3. Market Revenue and Forecast, by End User (2017-2030)
11.5.4. Brazil
11.5.4.1. Market Revenue and Forecast, by Service Type (2017-2030)
11.5.4.2. Market Revenue and Forecast, by Application (2017-2030)
11.5.4.3. Market Revenue and Forecast, by End User (2017-2030)
11.5.5. Rest of LATAM
11.5.5.1. Market Revenue and Forecast, by Service Type (2017-2030)
11.5.5.2. Market Revenue and Forecast, by Application (2017-2030)
11.5.5.3. Market Revenue and Forecast, by End User (2017-2030)
Chapter 12. Company Profiles
12.1. Thermo Fisher Scientific, Inc.
12.1.1. Company Overview
12.1.2. Product Offerings
12.1.3. Financial Performance
12.1.4. Recent Initiatives
12.2. Twist Bioscience
12.2.1. Company Overview
12.2.2. Product Offerings
12.2.3. Financial Performance
12.2.4. Recent Initiatives
12.3. Bioneer Corporation
12.3.1. Company Overview
12.3.2. Product Offerings
12.3.3. Financial Performance
12.3.4. Recent Initiatives
12.4. Eton Bioscience
12.4.1. Company Overview
12.4.2. Product Offerings
12.4.3. Financial Performance
12.4.4. Recent Initiatives
12.5. LGC Biosearch Technologie
12.5.1. Company Overview
12.5.2. Product Offerings
12.5.3. Financial Performance
12.5.4. Recent Initiatives
12.6. IBA GmbH
12.6.1. Company Overview
12.6.2. Product Offerings
12.6.3. Financial Performance
12.6.4. Recent Initiatives
12.7. Eurofins Scientific
12.7.1. Company Overview
12.7.2. Product Offerings
12.7.3. Financial Performance
12.7.4. Recent Initiatives
12.8. Integrated DNA Technologies, Inc.
12.8.1. Company Overview
12.8.2. Product Offerings
12.8.3. Financial Performance
12.8.4. Recent Initiatives
12.9. Quintara Biosciences
12.9.1. Company Overview
12.9.2. Product Offerings
12.9.3. Financial Performance
12.9.4. Recent Initiatives
12.10. GenScript Biotech Corporation
12.10.1. Company Overview
12.10.2. Product Offerings
12.10.3. Financial Performance
12.10.4. Recent Initiatives
Chapter 13. Research Methodology
13.1. Primary Research
13.2. Secondary Research
13.3. Assumptions
Chapter 14. Appendix
14.1. About Us
14.2. Glossary of Terms
Cross-segment Market Size and Analysis for
Mentioned Segments
Additional Company Profiles (Upto 5 With No Cost)
Additional Countries (Apart From Mentioned Countries)
Country/Region-specific Report
Go To Market Strategy
Region Specific Market DynamicsRegion Level Market Share Import Export AnalysisProduction AnalysisOthers