DNA Synthesizer Market Size, Growth, Trends, Report 2023-2032
The global DNA synthesizer market size was estimated at around USD 0.26 billion in 2022 and it is projected to hit around USD 1 billion by 2032, growing at a CAGR of 14.44% from 2023 to 2032. The DNA synthesizer market in the United States was accounted for USD 81.6 million in 2022.
Key Pointers
Report Scope of the DNA Synthesizer Market
| Report Coverage | Details |
| Revenue Share of North America in 2022 | 40% |
| CAGR of Asia Pacific from 2023 to 2032 | 15.94% |
| Revenue Forecast by 2032 | USD 1 billion |
| Growth Rate from 2023 to 2032 | CAGR of 14.44% |
| Base Year | 2022 |
| Forecast Period | 2023 to 2032 |
| Market Analysis (Terms Used) | Value (US$ Million/Billion) or (Volume/Units) |
| Companies Covered | Danaher; Twist Bioscience; Kilobaser; LGC Limited; CSBio; K&A Labs GmbH; DNA Script; OligoMaker ApS; PolyGen GmbH; Biolytic Lab Performance Inc. |
The increasing demand for efficient DNA synthesizers from life science laboratories, and pharmaceutical & biotechnology companies is the major factor driving the market. In addition, advancements in genomics and life sciences coupled with an increase in importance of DNA synthesizers in synthetic and molecular biology are other factors supporting market expansion. The outbreak of COVID-19 has had both negative and positive impact on the market. The COVID-19 pandemic boosted the demand for advanced synthesizers and related products as scientists developed potential diagnostics and treatments for COVID-19. On a contrary note, the pandemic had also a negative impact on market as it disrupted the research activities and manufacturing owing to restrictions and delays in supply of raw materials. However, after mid-2021, the market has witnessed a significant growth and is anticipated to expand at moderate growth rate owing to high demand for nucleic acid synthesis platforms across various end users.
Rising demand for novel synthesis technologies and technological advancements are the major factors driving the global market. Moreover, improvements in nucleic acid synthesis methods have opened new avenues for the market participants. For instance, SYNTAX STX-100 system developed by DNA Script is the first DNA printer powered by enzymatic synthesis that enables on-demand synthesis of custom oligos in a benchtop solution. Moreover, such synthesizers are equipped with enhanced speed and flexibility modules that enable technicians to create custom oligos in in less time.
Similarly, Kilobaser RNA and DNA synthesizer is developed to provide researchers across the globe with independent and unlimited access to vital life science tools. The chip and cartridge technology permits even untrained staff to quickly complete a successful RNA or DNA synthesis. In recent times, developing synthesizers with higher yields has gained momentum hence various manufacturers are engaged in manufacturing products with higher yield. For instance, market players like Biolytic, Cytiva, CsBio have developed synthesizers with higher yield capabilities.
Moreover, increasing demand for benchtop DNA synthesizers owing to its strong promise to increase speed & efficiency of research in academic and industrial labs is projected to increase their demand even more in forecast period. Thus, the rise in demand for benchtop solutions is pushing manufacturers to develop reliable benchtop systems. For instance, in June 2021 DNA Script announced the launch of SYNTAX system, the first benchtop nucleic acid printer powered by EDS technology to bolster genomics and molecular biology workflows. Such synthesizers are anticipated to boost market growth.
Furthermore, rising efforts to lower the cost of synthesizing DNA oligonucleotides and efforts to commercialize scalable DNA synthesizers have increased in recent times. Also, the use of microfluidic/microarray oligonucleotide synthesis methods and improvements in synthetic DNA quality have made great contribution toward this goal. In addition, increased market pressures, and continued development of other efficient synthesis technologies are further projected to increase the availability of inexpensive synthesizers.
Type Insights
The benchtop DNA synthesizers segment dominated the market in 2022 with a market share of 73%. Factors such as, increasing investment in R&D, growing demand for custom DNA synthesis, and robust demand from large range of end users are projected to drive segment growth. In addition, cost effectiveness of benchtop models is another factor responsible for its higher revenue share. Benchtop models are of small size and are less expensive than those of pilot scale synthesizers thus making them more feasible for small companies and research laboratories. Moreover, these synthesizers are commonly used for applications like PCR mutagenesis, gene cloning and site directed mutagenesis. Recent advancements in synthetic biology & genetics, recent product launches, and supportive government legislation are further driving the demand for synthesizers. For instance, in May 2022 EVONETIX LTD announced that it has been granted a patent for thermally controlled DNA synthesis. The patented technology can perform nucleic acid synthesis in a benchtop synthesizer platform.
Large-scale DNA synthesizers segment is expected to expand at a significant CAGR of 12.98% during 2023-2032. Robust demand from pharmaceutical & biotechnology companies, advances in DNA sequencing technologies, and the rising need for high-throughput screening are projected to fuel segment growth. The large-scale synthesizers are being increasingly utilized for high-throughput screening in drug discovery and this is likely to provide lucrative growth opportunities for the segment.
Application Insights
The drug discovery and development segment was the leading segment in 2022 with a revenue share of 49%. Wide application of DNA synthesizers in drug discovery, technology advancements, rising adoption of high-throughput technology, and presence of large number of market players with robust product portfolio are projected to fuel segment growth. Moreover, rising demand for advanced synthesis tools from drug companies to facilitate efficiency is another factor supporting segment expansion. For instance, in June 2022, Twist Bioscience announced its plans to remove limits on drug discovery with DNA synthesis platform. This helped company to expand its drug development capabilities.
The genetic engineering segment is projected to exhibit the fastest CAGR of 15.15% over the forecast period. Advancements in genetic engineering, rising availability of gene editing techniques like CRISPR/Cas9, and rising funding for commercializing novel interventions in genetic engineering are fueling segment uptake. Availability of several compact and laboratory scale synthesizers is also expected to boost the segment growth.
End use Insights
The pharmaceutical and biotechnology companies segment held the highest revenue share of 53% in 2022. Majority of pharma and biotech companies use synthetic DNA for developing novel genetic therapies, and for drug discovery process. Thus, the demand for synthesizers from biotechnology and pharmaceutical companies is projected to increase significantly in coming years due to rising need for precision medicine and novel therapeutic approaches. Moreover, leading market players emphasize on development, and implementation of novel platforms that can foster synthesis is another factor propelling segment growth. For instance, in February 2023 AstraZeneca automated its DNA synthesis capabilities to save cost and time. Also, according to Telesis Bio, automating DNA synthesis can boost drug discovery process. In addition, the company also mentioned that by automation the pharma and biotech firms can leverage and expand their pipeline.
The academic and research institutes segment is expected to expand at the fastest CAGR of 15.23% from 2023 to 2032. Growing areas of interest in research, ongoing efforts to develop novel synthesizers with higher yield capabilities, and collaboration between companies and research institutions are the factors expected to be responsible for growth of the segment. For instance, in January 2020, Evonetix collaborated with imec to foster chip-based technology manufacturing for third generation nucleic acid synthesis platform.
Regional Insights
North America accounted for the largest market share of 40% in 2022. The presence of large number of market players and various developments done by them is the key factor driving the region’s growth. Moreover, technological advancements, high investment in R&D, and rising demand for innovative synthesizers are other factors supporting regional market. Furthermore, the investments by market participants in the region is on the rise. For instance, in March 2022 Molecular Assemblies, Inc. raised USD 25.8 million series B financing to start key customer program for fully enzymatic DNA synthesis.
Asia Pacific is estimated to expand at a fastest CAGR of 15.94% from 2023 to 2032. This can be attributed to the surge in interest in synthetic biology research coupled with rising R&D efforts for the development of effective therapeutics. Moreover, APAC has a significant incidence of diseases due to lifestyle changes. Improving healthcare infrastructure, entry of large biotechnology organizations, and rising investments of market players in this region are also expected to contribute to the growth in demand for synthesizers.
DNA Synthesizer Market Segmentations:
By Type Scope
By Application Scope
By End use Scope
By Regional Scope
Chapter 1. Introduction
1.1. Research Objective
1.2. Scope of the Study
1.3. Definition
Chapter 2. Research Methodology
2.1. Research Approach
2.2. Data Sources
2.3. Assumptions & Limitations
Chapter 3. Executive Summary
3.1. Market Snapshot
Chapter 4. Market Variables and Scope
4.1. Introduction
4.2. Market Classification and Scope
4.3. Industry Value Chain Analysis
4.3.1. Raw Material Procurement Analysis
4.3.2. Sales and Distribution Type Scope Analysis
4.3.3. Downstream Buyer Analysis
Chapter 5. COVID 19 Impact on DNA Synthesizer Market
5.1. COVID-19 Landscape: DNA Synthesizer Industry Impact
5.2. COVID 19 - Impact Assessment for the Industry
5.3. COVID 19 Impact: Global Major Government Policy
5.4. Market Trends and Opportunities in the COVID-19 Landscape
Chapter 6. Market Dynamics Analysis and Trends
6.1. Market Dynamics
6.1.1. Market Drivers
6.1.2. Market Restraints
6.1.3. Market Opportunities
6.2. Porter’s Five Forces Analysis
6.2.1. Bargaining power of suppliers
6.2.2. Bargaining power of buyers
6.2.3. Threat of substitute
6.2.4. Threat of new entrants
6.2.5. Degree of competition
Chapter 7. Competitive Landscape
7.1.1. Company Market Share/Positioning Analysis
7.1.2. Key Strategies Adopted by Players
7.1.3. Vendor Landscape
7.1.3.1. List of Suppliers
7.1.3.2. List of Buyers
Chapter 8. Global DNA Synthesizer Market, By Type Scope
8.1. DNA Synthesizer Market, by Type Scope, 2023-2032
8.1.1 Benchtop DNA Synthesizers
8.1.1.1. Market Revenue and Forecast (2020-2032)
8.1.2. Large-scale DNA Synthesizers
8.1.2.1. Market Revenue and Forecast (2020-2032)
Chapter 9. Global DNA Synthesizer Market, By Application Scope
9.1. DNA Synthesizer Market, by Application Scope, 2023-2032
9.1.1. Drug Discovery & Development
9.1.1.1. Market Revenue and Forecast (2020-2032)
9.1.2. Genetic Engineering
9.1.2.1. Market Revenue and Forecast (2020-2032)
9.1.3. Clinical Diagnostics
9.1.3.1. Market Revenue and Forecast (2020-2032)
Chapter 10. Global DNA Synthesizer Market, By End use Scope
10.1. DNA Synthesizer Market, by End use Scope, 2023-2032
10.1.1. Academic & Research Institutes
10.1.1.1. Market Revenue and Forecast (2020-2032)
10.1.2. Pharmaceutical & Biotechnology Companies
10.1.2.1. Market Revenue and Forecast (2020-2032)
10.1.3. Clinical Laboratories
10.1.3.1. Market Revenue and Forecast (2020-2032)
Chapter 11. Global DNA Synthesizer Market, Regional Estimates and Trend Forecast
11.1. North America
11.1.1. Market Revenue and Forecast, by Type Scope (2020-2032)
11.1.2. Market Revenue and Forecast, by Application Scope (2020-2032)
11.1.3. Market Revenue and Forecast, by End use Scope (2020-2032)
11.1.4. U.S.
11.1.4.1. Market Revenue and Forecast, by Type Scope (2020-2032)
11.1.4.2. Market Revenue and Forecast, by Application Scope (2020-2032)
11.1.4.3. Market Revenue and Forecast, by End use Scope (2020-2032)
11.1.5. Rest of North America
11.1.5.1. Market Revenue and Forecast, by Type Scope (2020-2032)
11.1.5.2. Market Revenue and Forecast, by Application Scope (2020-2032)
11.1.5.3. Market Revenue and Forecast, by End use Scope (2020-2032)
11.2. Europe
11.2.1. Market Revenue and Forecast, by Type Scope (2020-2032)
11.2.2. Market Revenue and Forecast, by Application Scope (2020-2032)
11.2.3. Market Revenue and Forecast, by End use Scope (2020-2032)
11.2.4. UK
11.2.4.1. Market Revenue and Forecast, by Type Scope (2020-2032)
11.2.4.2. Market Revenue and Forecast, by Application Scope (2020-2032)
11.2.4.3. Market Revenue and Forecast, by End use Scope (2020-2032)
11.2.5. Germany
11.2.5.1. Market Revenue and Forecast, by Type Scope (2020-2032)
11.2.5.2. Market Revenue and Forecast, by Application Scope (2020-2032)
11.2.5.3. Market Revenue and Forecast, by End use Scope (2020-2032)
11.2.6. France
11.2.6.1. Market Revenue and Forecast, by Type Scope (2020-2032)
11.2.6.2. Market Revenue and Forecast, by Application Scope (2020-2032)
11.2.6.3. Market Revenue and Forecast, by End use Scope (2020-2032)
11.2.7. Rest of Europe
11.2.7.1. Market Revenue and Forecast, by Type Scope (2020-2032)
11.2.7.2. Market Revenue and Forecast, by Application Scope (2020-2032)
11.2.7.3. Market Revenue and Forecast, by End use Scope (2020-2032)
11.3. APAC
11.3.1. Market Revenue and Forecast, by Type Scope (2020-2032)
11.3.2. Market Revenue and Forecast, by Application Scope (2020-2032)
11.3.3. Market Revenue and Forecast, by End use Scope (2020-2032)
11.3.4. India
11.3.4.1. Market Revenue and Forecast, by Type Scope (2020-2032)
11.3.4.2. Market Revenue and Forecast, by Application Scope (2020-2032)
11.3.4.3. Market Revenue and Forecast, by End use Scope (2020-2032)
11.3.5. China
11.3.5.1. Market Revenue and Forecast, by Type Scope (2020-2032)
11.3.5.2. Market Revenue and Forecast, by Application Scope (2020-2032)
11.3.5.3. Market Revenue and Forecast, by End use Scope (2020-2032)
11.3.6. Japan
11.3.6.1. Market Revenue and Forecast, by Type Scope (2020-2032)
11.3.6.2. Market Revenue and Forecast, by Application Scope (2020-2032)
11.3.6.3. Market Revenue and Forecast, by End use Scope (2020-2032)
11.3.7. Rest of APAC
11.3.7.1. Market Revenue and Forecast, by Type Scope (2020-2032)
11.3.7.2. Market Revenue and Forecast, by Application Scope (2020-2032)
11.3.7.3. Market Revenue and Forecast, by End use Scope (2020-2032)
11.4. MEA
11.4.1. Market Revenue and Forecast, by Type Scope (2020-2032)
11.4.2. Market Revenue and Forecast, by Application Scope (2020-2032)
11.4.3. Market Revenue and Forecast, by End use Scope (2020-2032)
11.4.4. GCC
11.4.4.1. Market Revenue and Forecast, by Type Scope (2020-2032)
11.4.4.2. Market Revenue and Forecast, by Application Scope (2020-2032)
11.4.4.3. Market Revenue and Forecast, by End use Scope (2020-2032)
11.4.5. North Africa
11.4.5.1. Market Revenue and Forecast, by Type Scope (2020-2032)
11.4.5.2. Market Revenue and Forecast, by Application Scope (2020-2032)
11.4.5.3. Market Revenue and Forecast, by End use Scope (2020-2032)
11.4.6. South Africa
11.4.6.1. Market Revenue and Forecast, by Type Scope (2020-2032)
11.4.6.2. Market Revenue and Forecast, by Application Scope (2020-2032)
11.4.6.3. Market Revenue and Forecast, by End use Scope (2020-2032)
11.4.7. Rest of MEA
11.4.7.1. Market Revenue and Forecast, by Type Scope (2020-2032)
11.4.7.2. Market Revenue and Forecast, by Application Scope (2020-2032)
11.4.7.3. Market Revenue and Forecast, by End use Scope (2020-2032)
11.5. Latin America
11.5.1. Market Revenue and Forecast, by Type Scope (2020-2032)
11.5.2. Market Revenue and Forecast, by Application Scope (2020-2032)
11.5.3. Market Revenue and Forecast, by End use Scope (2020-2032)
11.5.4. Brazil
11.5.4.1. Market Revenue and Forecast, by Type Scope (2020-2032)
11.5.4.2. Market Revenue and Forecast, by Application Scope (2020-2032)
11.5.4.3. Market Revenue and Forecast, by End use Scope (2020-2032)
11.5.5. Rest of LATAM
11.5.5.1. Market Revenue and Forecast, by Type Scope (2020-2032)
11.5.5.2. Market Revenue and Forecast, by Application Scope (2020-2032)
11.5.5.3. Market Revenue and Forecast, by End use Scope (2020-2032)
Chapter 12. Company Profiles
12.1. Danaher
12.1.1. Company Overview
12.1.2. Product Offerings
12.1.3. Financial Performance
12.1.4. Recent Initiatives
12.2. Twist Bioscience.
12.2.1. Company Overview
12.2.2. Product Offerings
12.2.3. Financial Performance
12.2.4. Recent Initiatives
12.3. Kilobaser.
12.3.1. Company Overview
12.3.2. Product Offerings
12.3.3. Financial Performance
12.3.4. Recent Initiatives
12.4. LGC Limited
12.4.1. Company Overview
12.4.2. Product Offerings
12.4.3. Financial Performance
12.4.4. Recent Initiatives
12.5. CSBio
12.5.1. Company Overview
12.5.2. Product Offerings
12.5.3. Financial Performance
12.5.4. Recent Initiatives
12.6. K&A Labs GmbH
12.6.1. Company Overview
12.6.2. Product Offerings
12.6.3. Financial Performance
12.6.4. Recent Initiatives
12.7. DNA Script.
12.7.1. Company Overview
12.7.2. Product Offerings
12.7.3. Financial Performance
12.7.4. Recent Initiatives
12.8. OligoMaker ApS
12.8.1. Company Overview
12.8.2. Product Offerings
12.8.3. Financial Performance
12.8.4. Recent Initiatives
12.9. PolyGen GmbH
12.9.1. Company Overview
12.9.2. Product Offerings
12.9.3. Financial Performance
12.9.4. Recent Initiatives
12.10. Biolytic Lab Performance Inc.
12.10.1. Company Overview
12.10.2. Product Offerings
12.10.3. Financial Performance
12.10.4. Recent Initiatives
Chapter 13. Research Methodology
13.1. Primary Research
13.2. Secondary Research
13.3. Assumptions
Chapter 14. Appendix
14.1. About Us
14.2. Glossary of Terms
Cross-segment Market Size and Analysis for
Mentioned Segments
Additional Company Profiles (Upto 5 With No Cost)
Additional Countries (Apart From Mentioned Countries)
Country/Region-specific Report
Go To Market Strategy
Region Specific Market DynamicsRegion Level Market Share Import Export AnalysisProduction AnalysisOthers