Metagenomics Market (By Technology: Shotgun Sequencing, Whole Genome Sequencing; By Product; By Workflow; By Application) - Global Industry Analysis, Size, Share, Growth, Trends, Revenue, Regional Outlook and Forecast 2024-2033

The global metagenomics market size was estimated at around USD 2.05 billion in 2023 and it is projected to hit around USD 7.31 billion by 2033, growing at a CAGR of 13.55% from 2024 to 2033.

Key Pointers

• North America led the global market with the largest market share of 41% in 2023.
• Asia Pacific is expected to exhibit the fastest CAGR from 2024 to 2033.
• By Product, the segment for kits and reagents held the largest revenue share of 62% in 2023.
• By Product, the sequencing and data analytics services segment is expected to expand at the highest CAGR from 2024 to 2033.
• By Technology, the shotgun sequencing segment generated the maximum market share of 35% in 2023.
• By Technology, the 16S sequencing segment is expected to experience significant growth during the forecast period.
• By Workflow, the sequencing segment captured the maximum market share of 54% in 2023.
• By Workflow, the data analysis segment is expected to grow at the fastest CAGR over the forecast period.
• By Application, the environmental segment contributed the largest market share of 26% in 2023.

Metagenomics Market Overview

Metagenomics, a cutting-edge field within genomics, has emerged as a pivotal tool in understanding the complex microbial communities inhabiting diverse ecosystems. This innovative approach transcends traditional sequencing methods by enabling the comprehensive study of microbial genetic material directly from environmental samples. The Metagenomics Market, characterized by rapid advancements and expanding applications, offers promising opportunities for research, diagnostics, and therapeutic development.

Metagenomics Market Growth Factors

The growth of the Metagenomics Market is propelled by an increasing recognition of the pivotal role played by microbial communities in various ecosystems, including human health and disease, is driving demand for metagenomic research. Advancements in sequencing technologies have significantly lowered costs and improved efficiency, making metagenomic analysis more accessible to researchers and industry players alike. Additionally, the expanding scope of metagenomics beyond microbial ecology to areas such as personalized medicine, agriculture, and environmental monitoring is creating new avenues for market growth. These factors, combined with growing investments in research and development, are fueling the expansion of the Metagenomics Market and its potential to revolutionize diverse sectors.

U.S. Metagenomics Market Size 2024 to 2033

The U.S. metagenomics market size was valued at USD 0.58 billion in 2023 and is predicted to surpass around USD 2.09 billion by 2033 with a CAGR of 13.67% from 2024 to 2033.

This can be credited to extensive genomics, oncology, and whole-genome sequencing research in the country. Other contributing factors include sophisticated research and medical infrastructure, ample funding, a skilled workforce, and companies pushing for improved research methods to identify newer technologies for diagnosis and therapies.

North America emerged as the dominant player in the metagenomics market in 2023, capturing a revenue share of 41%. This dominance is attributed to several factors, including the presence of key companies, increased research and development funding, and advancements in sequencing technology. Collaborations between companies and academic institutions are a prominent strategy driving growth in the region. For instance, in September 2021, The Broad Institute collaborated with the CDC and Theiagen Genomics to enhance support for public health laboratories in the U.S., particularly focusing on nationwide pathogen genomics surveillance.

In contrast, Asia Pacific is expected to exhibit the fastest compound annual growth rate (CAGR) during the forecast period. This growth is propelled by substantial advancements in metagenomics adoption across diverse applications, particularly in India and China. The region's focus on genomics and proteomics research, coupled with proactive initiatives from academic institutions to advance sequencing technologies, presents lucrative growth opportunities throughout the forecast period.

Metagenomics Market Trends:

• Integration of Multi-Omics Approaches: Metagenomics is increasingly being integrated with other omics disciplines such as metatranscriptomics, metaproteomics, and metabolomics. This holistic approach enables comprehensive analysis of microbial communities and their functional activities, providing deeper insights into ecosystem dynamics, host-microbe interactions, and disease mechanisms.
• Artificial Intelligence (AI) and Machine Learning (ML) in Data Analysis: The complexity of metagenomic data necessitates advanced computational tools for analysis and interpretation. AI and ML algorithms are being deployed to streamline data processing, identify microbial signatures, predict biological functions, and uncover novel associations within complex datasets. These technologies hold promise for accelerating discovery and enabling personalized interventions based on metagenomic insights.
• Decentralized Sequencing Platforms: Traditional centralized sequencing facilities have limitations in terms of turnaround time, cost, and accessibility. The emergence of portable, benchtop sequencing devices is democratizing metagenomic analysis, enabling real-time monitoring of microbial communities in diverse settings such as clinics, field sites, and point-of-care settings. These decentralized platforms empower researchers and clinicians with on-demand metagenomic capabilities, facilitating rapid decision-making and intervention strategies.
• Microbiome-Based Therapeutics: Advances in metagenomics are driving the development of microbiome-based therapeutics, also known as microbiome drugs or live biotherapeutics. By leveraging insights from metagenomic profiling, researchers can identify microbial targets associated with specific diseases and engineer probiotic formulations to modulate the microbiome and restore microbial balance. This personalized approach holds promise for treating various disorders, including gastrointestinal conditions, metabolic disorders, and immune-related diseases.
• Environmental Monitoring and Bioremediation: Metagenomics is increasingly being applied in environmental monitoring and bioremediation efforts. By characterizing microbial communities in soil, water, and air samples, metagenomic analysis provides valuable information about ecosystem health, pollutant degradation pathways, and microbial responses to environmental changes. This knowledge informs strategies for mitigating pollution, restoring ecosystems, and promoting sustainable environmental management practices.

Product Insights

The segment for kits and reagents dominated the revenue share, accounting for over 62% in 2023. These kits and reagents are tailored for specific purposes such as analyzing soil, water, and biological samples. They find extensive use in screening various microbial entities like bacteria, viruses, pathogens, fungi, and micro-eukaryotic species as per the study's requirements. Consequently, the introduction of innovative kits employing these techniques for tasks like library preparation, Polymerase Chain Reaction (PCR) assays, and other assays is expected to propel growth within this segment.

Furthermore, the sequencing and data analytics services segment is anticipated to exhibit significant growth during the forecast period. The increased adoption of sequencing technologies has led to a heightened demand for platforms facilitating data analysis. Simultaneously, companies are either providing services for interpreting metagenomics data or launching products to engage research entities in clinical applications.

Technology Insights

The shotgun sequencing segment dominated with the largest revenue share, accounting for 35% in 2023. This technique involves sequencing entire genomes by randomly fragmenting DNA into small pieces and then sequencing each fragment. It finds extensive applications in genomics research, clinical diagnostics, and various industries including environmental monitoring and conservation, as well as agriculture and crop improvement. Moreover, in clinical settings, shotgun sequencing plays a vital role in identifying genetic mutations associated with diseases and facilitating personalized treatment plans.

The 16S sequencing segment is expected to experience significant growth during the forecast period. This technique, commonly used in microbial ecology studies, aids in understanding microbial diversity. The rising interest in exploring the human microbiome and microbial communities in diverse environments has fueled the demand for methods like 16S sequencing and metagenomics. Additionally, 16S sequencing contributes to the discovery of novel bioactive compounds from environmental samples, thereby bolstering drug discovery and biotechnological applications.

Workflow Insights

The sequencing segment emerged as the market leader, capturing a revenue share of 54% in 2023. This growth is primarily attributed to the cost-effectiveness and enhanced accuracy achieved through technological advancements in sequencing. Companies routinely integrate sequencing methods into genetic research, a pivotal aspect of genetic testing. For instance, in June 2023, Delve Bio introduced a novel metagenomic sequencing platform tailored for diagnosing infectious diseases.

Conversely, the data analysis segment is poised to exhibit a lucrative compound annual growth rate (CAGR) over the forecast period. This projection stems from the pivotal role of data analysis in deciphering complex biological information. Data analysis is instrumental in extracting meaningful patterns, identifying crucial microbial species, and unraveling functional insights from genomic data. The ability to unveil intricate details regarding microbial interactions, community dynamics, and functional potential significantly enhances the impact of metagenomic research. Consequently, the overall demand for data analysis is anticipated to surge during the forecast period.

Application Insights

In 2023, the environmental segment emerged as the market leader, commanding a revenue share of 26%. Metagenomics research is rapidly expanding its role in agriculture and environmental protection by employing sequencing analysis or gene screening to understand microorganisms within specific environments. This approach marks a novel way of comprehending microbial ecosystems. Additionally, environmental metagenomics analysis is employed in studying ecological remediation, agricultural microbiome analysis, oceanic oil spills, and other biological investigations. The integration of genome-centric metagenomics analysis with single-cell genomics provides access to unprecedented genomic information about microbes.

On the other hand, the clinical diagnostics segment is poised to exhibit a lucrative compound annual growth rate (CAGR) over the forecast period. In clinical diagnostics, metagenomics utilizes advanced genomic technologies to examine the genetic material of microbial communities present in clinical samples. This method revolutionizes pathogen detection by offering a holistic perspective on various pathogens, including bacteria, viruses, fungi, and parasites, thus overcoming the limitations of conventional diagnostic techniques.

Metagenomics Market Key Companies

• Bio-Rad Laboratories, Inc
• Illumina, Inc.
• PerkinElmer, Inc.
• Thermo Fisher Scientific, Inc.
• Novogene Co., Ltd.
• Promega Corporation
• QIAGEN
• Takara Bio, Inc.
• Oxford Nanopore Technologies
• F. Hoffmann-La Roche Ltd.

Metagenomics Market Segmentations:

By Product

• Kits & Reagents
• Sequencing & Data Analytics Services
• Software

By Technology

• Shotgun Sequencing
• 16S Sequencing
• Whole Genome Sequencing
• Others

By Workflow

• Pre-sequencing
• Sequencing
• Data Analysis

By Application

• Environmental
• Clinical Diagnostics
• Drug Discovery
• Biotechnology
• Food & nutrition
• Others

By Region

• North America
• Europe
• Asia Pacific
• Latin America
• Middle East & Africa