The global protein crystallization market size was estimated at around USD 1.2 billion in 2021 and it is projected to hit around USD 2.63 billion by 2030, growing at a CAGR of 9.1% from 2022 to 2030.
Crystallization is the process of the formation of 3D structured molecule from a liquid substance. Protein crystallization is the process of the formation of pure and saturated protein crystals containing millions of protein molecules arranged in an orderly manner. The proteins are dissolved in the aqueous sample solution until they become supersaturated. For this purpose, the methods such as microdialysis, and diffusion are used. Crystallization of proteins is also a technique for purification. These crystallized proteins are used for X-ray crystallography.
Scope of The Report
Report Coverage | Details |
Market Size in 2021 | USD 1.2 billion |
Revenue Forecast by 2030 | USD 2.63 billion |
Growth rate from 2022 to 2030 | CAGR of 9.1% |
Base Year | 2021 |
Forecast Period | 2022 to 2030 |
Segmentation | Type, Technology, Application, End user, Region |
Companies Covered |
Rigaku Corporation, Hampton Research Corp, HiMedia Laboratories, Bruker Corporation, Thermo Fisher Scientific, Inc., Jena Bioscience GmbH, Agilent Technologies, Charles River Laboratories, Inc., Molecular Dimensions Ltd., Formulatrix, Inc., MiTeGen LLC |
Following are the steps of protein crystallization:-
The important applications of crystallization are:-
1. Medical chemistry via studying the structural biology (study of drug receptor interaction to improve drug efficacy),
2. Developing, scaling up, purification, and separation of therapeutic proteins,
3. Formulation and drug delivery.
The rise in infectious diseases has boosted the demand for the production and development of therapeutic products and vaccine development. Therapeutic proteins have a wide range of applications in treating cancer. The increasing prevalence of cancer disease spurs the market growth.
The increasing number of product launches and increasing efforts to find the solution for the diagnosis and treatment of chronic diseases by the biotechnology and pharmaceutical industries also has a positive impact on the market. In July 2022, Redwire Corporation announced that it would develop new manufacturing techniques for the development of small pharmaceutical protein crystals and other molecules for R&D and production. The high resolution imaging of the crystal structures provides the precise results which fuels the crystallization market. However, a lack of qualified researchers for handling crystallization protocol can hamper the market growth.
The crystallization market is segmented based on type, technology, application, end-use, and region. The type segment is further segmented into consumables, reagent kits, instruments, software, and services. The technology segment is divided into small-angle X-ray scattering, X-ray crystallography, cryo-electron microscopy, NMR spectroscopy. The application segment is divided into therapeutic protein production, drug delivery, and medical chemistry. End use segment is classified into pharmaceutical companies, biotechnology companies, and others.
Based on regional analysis the market is segmented into North America, Europe, Asia-Pacific, Latin America, the Middle East, and Africa. North America holds the major share in crystallization market. This is due to the increase in R&D investments and collaboration by the major key players in this region. Also, the increased government funding for proteomic research and the development of structure-based drugs enhances the market growth. Asia Pacific and Europe also have high investments in the R&D sector by the key players of pharmaceutical and biotechnology company which boost the crystallization technology.
Major companies operating in the protein crystallization market include Rigaku Corporation, Hampton Research Corp, HiMedia Laboratories, Bruker Corporation, Thermo Fisher Scientific, Inc., Jena Bioscience GmbH, Agilent Technologies, Charles River Laboratories, Inc., Molecular Dimensions Ltd., Formulatrix, Inc., MiTeGen LLC among others.
Market Segmentation
By Type Outlook
By Technology Outlook
By Application Outlook
By End user Outlook
By Region Outlook
Chapter 1. Introduction
1.1. Research Objective
1.2. Scope of the Study
1.3. Definition
Chapter 2. Research Methodology
2.1. Research Approach
2.2. Data Sources
2.3. Assumptions & Limitations
Chapter 3. Executive Summary
3.1. Market Snapshot
Chapter 4. Market Variables and Scope
4.1. Introduction
4.2. Market Classification and Scope
4.3. Industry Value Chain Analysis
4.3.1. Raw Material Procurement Analysis
4.3.2. Sales and Distribution Channel Analysis
4.3.3. Downstream Buyer Analysis
Chapter 5. COVID 19 Impact on Protein Crystallization Market
5.1. COVID-19 Landscape: Protein Crystallization Industry Impact
5.2. COVID 19 - Impact Assessment for the Industry
5.3. COVID 19 Impact: Global Major Government Policy
5.4. Market Trends and Opportunities in the COVID-19 Landscape
Chapter 6. Market Dynamics Analysis and Trends
6.1. Market Dynamics
6.1.1. Market Drivers
6.1.2. Market Restraints
6.1.3. Market Opportunities
6.2. Porter’s Five Forces Analysis
6.2.1. Bargaining power of suppliers
6.2.2. Bargaining power of buyers
6.2.3. Threat of substitute
6.2.4. Threat of new entrants
6.2.5. Degree of competition
Chapter 7. Competitive Landscape
7.1.1. Company Market Share/Positioning Analysis
7.1.2. Key Strategies Adopted by Players
7.1.3. Vendor Landscape
7.1.3.1. List of Suppliers
7.1.3.2. List of Buyers
Chapter 8. Global Protein Crystallization Market, By Type
8.1. Protein Crystallization Market, by Type, 2022-2030
8.1.1. Consumables
8.1.1.1. Market Revenue and Forecast (2017-2030)
8.1.2. Reagent Kits
8.1.2.1. Market Revenue and Forecast (2017-2030)
8.1.3. Instruments
8.1.3.1. Market Revenue and Forecast (2017-2030)
8.1.4. Software and Services
8.1.4.1. Market Revenue and Forecast (2017-2030)
Chapter 9. Global Protein Crystallization Market, By Technology
9.1. Protein Crystallization Market, by Technology, 2022-2030
9.1.1. X-ray Crystallography
9.1.1.1. Market Revenue and Forecast (2017-2030)
9.1.2. NMR Spectroscopy
9.1.2.1. Market Revenue and Forecast (2017-2030)
9.1.3. Cryo-electron Microscopy
9.1.3.1. Market Revenue and Forecast (2017-2030)
9.1.4. Small-angle X-ray Scattering (SAXS)
9.1.4.1. Market Revenue and Forecast (2017-2030)
Chapter 10. Global Protein Crystallization Market, By Application
10.1. Protein Crystallization Market, by Application, 2022-2030
10.1.1. Therapeutic protein production
10.1.1.1. Market Revenue and Forecast (2017-2030)
10.1.2. Drug delivery
10.1.2.1. Market Revenue and Forecast (2017-2030)
10.1.3. Medical chemistry
10.1.3.1. Market Revenue and Forecast (2017-2030)
10.1.4. Others
10.1.4.1. Market Revenue and Forecast (2017-2030)
Chapter 11. Global Protein Crystallization Market, By End user
11.1. Protein Crystallization Market, by End user, 2022-2030
11.1.1. Pharmaceutical Company
11.1.1.1. Market Revenue and Forecast (2017-2030)
11.1.2. Biotechnology Company
11.1.2.1. Market Revenue and Forecast (2017-2030)
11.1.3. Others
11.1.3.1. Market Revenue and Forecast (2017-2030)
Chapter 12. Global Protein Crystallization Market, Regional Estimates and Trend Forecast
12.1. North America
12.1.1. Market Revenue and Forecast, by Type (2017-2030)
12.1.2. Market Revenue and Forecast, by Technology (2017-2030)
12.1.3. Market Revenue and Forecast, by Application (2017-2030)
12.1.4. Market Revenue and Forecast, by End user (2017-2030)
12.1.5. U.S.
12.1.5.1. Market Revenue and Forecast, by Type (2017-2030)
12.1.5.2. Market Revenue and Forecast, by Technology (2017-2030)
12.1.5.3. Market Revenue and Forecast, by Application (2017-2030)
12.1.5.4. Market Revenue and Forecast, by End user (2017-2030)
12.1.6. Rest of North America
12.1.6.1. Market Revenue and Forecast, by Type (2017-2030)
12.1.6.2. Market Revenue and Forecast, by Technology (2017-2030)
12.1.6.3. Market Revenue and Forecast, by Application (2017-2030)
12.1.6.4. Market Revenue and Forecast, by End user (2017-2030)
12.2. Europe
12.2.1. Market Revenue and Forecast, by Type (2017-2030)
12.2.2. Market Revenue and Forecast, by Technology (2017-2030)
12.2.3. Market Revenue and Forecast, by Application (2017-2030)
12.2.4. Market Revenue and Forecast, by End user (2017-2030)
12.2.5. UK
12.2.5.1. Market Revenue and Forecast, by Type (2017-2030)
12.2.5.2. Market Revenue and Forecast, by Technology (2017-2030)
12.2.5.3. Market Revenue and Forecast, by Application (2017-2030)
12.2.5.4. Market Revenue and Forecast, by End user (2017-2030)
12.2.6. Germany
12.2.6.1. Market Revenue and Forecast, by Type (2017-2030)
12.2.6.2. Market Revenue and Forecast, by Technology (2017-2030)
12.2.6.3. Market Revenue and Forecast, by Application (2017-2030)
12.2.6.4. Market Revenue and Forecast, by End user (2017-2030)
12.2.7. France
12.2.7.1. Market Revenue and Forecast, by Type (2017-2030)
12.2.7.2. Market Revenue and Forecast, by Technology (2017-2030)
12.2.7.3. Market Revenue and Forecast, by Application (2017-2030)
12.2.7.4. Market Revenue and Forecast, by End user (2017-2030)
12.2.8. Rest of Europe
12.2.8.1. Market Revenue and Forecast, by Type (2017-2030)
12.2.8.2. Market Revenue and Forecast, by Technology (2017-2030)
12.2.8.3. Market Revenue and Forecast, by Application (2017-2030)
12.2.8.4. Market Revenue and Forecast, by End user (2017-2030)
12.3. APAC
12.3.1. Market Revenue and Forecast, by Type (2017-2030)
12.3.2. Market Revenue and Forecast, by Technology (2017-2030)
12.3.3. Market Revenue and Forecast, by Application (2017-2030)
12.3.4. Market Revenue and Forecast, by End user (2017-2030)
12.3.5. India
12.3.5.1. Market Revenue and Forecast, by Type (2017-2030)
12.3.5.2. Market Revenue and Forecast, by Technology (2017-2030)
12.3.5.3. Market Revenue and Forecast, by Application (2017-2030)
12.3.5.4. Market Revenue and Forecast, by End user (2017-2030)
12.3.6. China
12.3.6.1. Market Revenue and Forecast, by Type (2017-2030)
12.3.6.2. Market Revenue and Forecast, by Technology (2017-2030)
12.3.6.3. Market Revenue and Forecast, by Application (2017-2030)
12.3.6.4. Market Revenue and Forecast, by End user (2017-2030)
12.3.7. Japan
12.3.7.1. Market Revenue and Forecast, by Type (2017-2030)
12.3.7.2. Market Revenue and Forecast, by Technology (2017-2030)
12.3.7.3. Market Revenue and Forecast, by Application (2017-2030)
12.3.7.4. Market Revenue and Forecast, by End user (2017-2030)
12.3.8. Rest of APAC
12.3.8.1. Market Revenue and Forecast, by Type (2017-2030)
12.3.8.2. Market Revenue and Forecast, by Technology (2017-2030)
12.3.8.3. Market Revenue and Forecast, by Application (2017-2030)
12.3.8.4. Market Revenue and Forecast, by End user (2017-2030)
12.4. MEA
12.4.1. Market Revenue and Forecast, by Type (2017-2030)
12.4.2. Market Revenue and Forecast, by Technology (2017-2030)
12.4.3. Market Revenue and Forecast, by Application (2017-2030)
12.4.4. Market Revenue and Forecast, by End user (2017-2030)
12.4.5. GCC
12.4.5.1. Market Revenue and Forecast, by Type (2017-2030)
12.4.5.2. Market Revenue and Forecast, by Technology (2017-2030)
12.4.5.3. Market Revenue and Forecast, by Application (2017-2030)
12.4.5.4. Market Revenue and Forecast, by End user (2017-2030)
12.4.6. North Africa
12.4.6.1. Market Revenue and Forecast, by Type (2017-2030)
12.4.6.2. Market Revenue and Forecast, by Technology (2017-2030)
12.4.6.3. Market Revenue and Forecast, by Application (2017-2030)
12.4.6.4. Market Revenue and Forecast, by End user (2017-2030)
12.4.7. South Africa
12.4.7.1. Market Revenue and Forecast, by Type (2017-2030)
12.4.7.2. Market Revenue and Forecast, by Technology (2017-2030)
12.4.7.3. Market Revenue and Forecast, by Application (2017-2030)
12.4.7.4. Market Revenue and Forecast, by End user (2017-2030)
12.4.8. Rest of MEA
12.4.8.1. Market Revenue and Forecast, by Type (2017-2030)
12.4.8.2. Market Revenue and Forecast, by Technology (2017-2030)
12.4.8.3. Market Revenue and Forecast, by Application (2017-2030)
12.4.8.4. Market Revenue and Forecast, by End user (2017-2030)
12.5. Latin America
12.5.1. Market Revenue and Forecast, by Type (2017-2030)
12.5.2. Market Revenue and Forecast, by Technology (2017-2030)
12.5.3. Market Revenue and Forecast, by Application (2017-2030)
12.5.4. Market Revenue and Forecast, by End user (2017-2030)
12.5.5. Brazil
12.5.5.1. Market Revenue and Forecast, by Type (2017-2030)
12.5.5.2. Market Revenue and Forecast, by Technology (2017-2030)
12.5.5.3. Market Revenue and Forecast, by Application (2017-2030)
12.5.5.4. Market Revenue and Forecast, by End user (2017-2030)
12.5.6. Rest of LATAM
12.5.6.1. Market Revenue and Forecast, by Type (2017-2030)
12.5.6.2. Market Revenue and Forecast, by Technology (2017-2030)
12.5.6.3. Market Revenue and Forecast, by Application (2017-2030)
12.5.6.4. Market Revenue and Forecast, by End user (2017-2030)
Chapter 13. Company Profiles
13.1. Rigaku Corporation
13.1.1. Company Overview
13.1.2. Product Offerings
13.1.3. Financial Performance
13.1.4. Recent Initiatives
13.2. Hampton Research Corp
13.2.1. Company Overview
13.2.2. Product Offerings
13.2.3. Financial Performance
13.2.4. Recent Initiatives
13.3. HiMedia Laboratories
13.3.1. Company Overview
13.3.2. Product Offerings
13.3.3. Financial Performance
13.3.4. Recent Initiatives
13.4. Bruker Corporation
13.4.1. Company Overview
13.4.2. Product Offerings
13.4.3. Financial Performance
13.4.4. Recent Initiatives
13.5. Thermo Fisher Scientific, Inc.
13.5.1. Company Overview
13.5.2. Product Offerings
13.5.3. Financial Performance
13.5.4. Recent Initiatives
13.6. Jena Bioscience GmbH
13.6.1. Company Overview
13.6.2. Product Offerings
13.6.3. Financial Performance
13.6.4. Recent Initiatives
13.7. Agilent Technologies
13.7.1. Company Overview
13.7.2. Product Offerings
13.7.3. Financial Performance
13.7.4. Recent Initiatives
13.8. Charles River Laboratories, Inc.
13.8.1. Company Overview
13.8.2. Product Offerings
13.8.3. Financial Performance
13.8.4. Recent Initiatives
13.9. Molecular Dimensions Ltd.
13.9.1. Company Overview
13.9.2. Product Offerings
13.9.3. Financial Performance
13.9.4. Recent Initiatives
13.10. Formulatrix, Inc.
13.10.1. Company Overview
13.10.2. Product Offerings
13.10.3. Financial Performance
13.10.4. Recent Initiatives
Chapter 14. Research Methodology
14.1. Primary Research
14.2. Secondary Research
14.3. Assumptions
Chapter 15. Appendix
15.1. About Us
15.2. Glossary of Terms