Rat Model Market Size, Share, Trends, Growth, Production, Consumption, Revenue, Company Analysis and Forecast 2022-2030

The global Rat Model market size is expected to be worth around US$ 1845 Million by 2030, according to a new report by Vision Research Reports.

The global Rat Model market size was valued at US$ 524.3 Million in 2021 and is anticipated to grow at a CAGR of 18.3% during forecast period 2022 to 2030.

Growth Factors

The outbred type of rat model is commonly utilized for research and educational activities within the healthcare domain. However, advancement in production technologies is expected to boost the growth of knockout and conditioned rats. The production technologies for the aforementioned type of model are recent in nature and can be traced back to 2008, post the development of mobile DNA technology.

The first knockout model was introduced in 2009 using the Zinc Finger Nuclease (ZFN) method, which led to an advancement in the field of rat models. Other tools for genetic editing are Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR), homologous recombination, and N-ethyl-N-nitrosourea (ENU) mutagenesis. Furthermore, supportive infrastructure and technology coupled with the growing incidence of chronic conditions & genetic mutation amongst human species are expected to extend higher applicability for research purposes, thereby boosting growth.

Type Insights

The outbred segment held the largest revenue share of over 25.0% in 2021. The outbred rats represent the genetic variations of humans more accurately, resulting in their vast use during preclinical research. This contributes to the larger share of outbred models. These outbred rats are phenotypically stable to a certain extent and also are less susceptible to differences in the environment, making them a right fit to mimic the genetic variations that eventually result in diseases. Key players such as Charles River Laboratories International Inc. have implemented genetic management programs for their rodent models in line with the InternationalGenetic Standardization (IGS) program. This program ensures that rat models produced across the globe are of the same genetic profile.

The inbred segment accounted for a considerable share in 2021. The predominant use of the inbred rat model in toxicology studies and stable genome structure are facilitating the growth of the segment. A toxicology study using a small number of inbred models of different strains can provide extensive data. Knockout strain is estimated to witness the fastest growth in the forecast period. The advent of genome editing tools has facilitated the generation of knockout rat models. Moreover, owing to the presence of multiple players with a reduced turnaround time for the knockout model, it is expected to observe lucrative growth during the forecast period.

Technology Insights

The other technologies segment held the largest revenue share of over 30.0% in 2021. The other technologies include CRISPR/CAS, ZFN, TALEN, and RNAi, among many others. The developments in synthetic biology and increased application of gene editing tools of aforementioned technologies among many other technologies during model creation are contributing to the segment growth. The ease of genetic manipulation via these molecular tools facilitates the rat model creation procedure efficiently with a shorter timeline for research breakthroughs.

Additionally, during the projected period, advanced genome editing tools are likely to observe the fastest growth. With the recognition of CRISPR-Cas9 in the 2020 Nobel Prize in Chemistry, biomedical research has been revolutionized. This editing tool has been employed to establish multiple rat models, which are used for drug-related studies. For instance, as per a review article published in October 2021, a series of knockout rat models has been generated for DMPK (drug metabolism and pharmacokinetics) studies by using the CRISPR-Cas9 method.

Furthermore, the use of microinjection to introduce these nucleases directly into the fertilized embryos eliminates the need for stem cell altercations and saves time. Companies are capitalizing on this market trend and offering custom rat model generation services. The model generation services are mediated by these aforementioned technologies, which is ultimately boosting revenue generation in the market.

Service Insights

In 2021, breeding services held the largest share of over 30.0%. This is due to the increased demand for the rat model for experiments and research studies. The similarity in genome structure, behaviors, and easy handling are a few of the factors that contribute to the growth of the breeding segment. Moreover, the presence of inbred and outbred models to generate different genetic profiles contribute to revenue generation within this segment. Their wide application in various advanced research often requires mating schemes and genome management programs in rodent handling facilities, which further drives the market.

The cryopreservation service segment is estimated to be the fastest-growing segment in the forecast period. This service includes the ultra-freezing of embryos, sperms, and even research strains of the rat, and creates a cost-effective plan to store and back up the required models with anticipated future use. These cryoservices also offer protection to the intended model in case of contamination, natural calamity, unintentional accident, and gene alteration or drift in later generations. Furthermore, the ease of recovering these cryopreserved stocks in 10-12 weeks drives the segment. For example, in a January 2020 published scientific article, researchers from Japan developed a satisfactory protocol for both cryopreservation of rat sperm and in-vitro fertilization. It was even demonstrated in the study that these frozen sperms yielded high fertilization rates.

Application Insights

The toxicology segment held the largest revenue share of over 30.0% in 2021. Continuous demand for medicines and therapies led to growing investments by both government and key healthcare players. This never-ceasing demand for innovative medications and therapeutics drives research activities to advance the health infrastructure. During the preclinical stage of any drug development, the rat model is employed in toxicology studies to assess the dosing regimen, optimal dose, route of administration, and many other parameters. Moreover, during these studies, the rat model helps in analyzing the functioning of organs and protein expression approaches during human treatments. Due to these factors, the application of the rat model in toxicology is massive.

The immunology segment is expected to grow at the fastest rate from 2022 to 2030 owing to the increase in chronic and infectious diseases. The COVID-19 pandemic also increased research activities and drug development required a huge number of rat models. This was because as directed by the US FDA, it is required to verify the efficacy and safety of new candidates in animals before directing them to human clinical trials. Additionally, the development of multiple vaccines all across the globe for the COVID-19 virus demonstrates the usage rate of rats. Such importance of animal models in research and development programs bolsters the future growth of the market.

End-use Insights

CROs held the largest revenue share of over 45.0% in 2021. This can be attributed to increased outsourcing of preclinical and clinical testing by healthcare companies and the consequent rise in the number of CROs. With the presence of multiple product development programs and an aim to increase the market entry speed, pharma and biotech companies usually outsource their trials and testing on rat models to CROs. Moreover, the well-equipped facilities, trained professionals, and legal compliances in places make CROs an attractive option, thus contributing to the lucrative growth of the segment.

The pharmaceutical and biotechnology companies segment is expected to witness growth in the coming years. The increased application of the rat model during the R&D pipeline and the production of drugs and vaccines for autoimmune disorders and infectious diseases have boosted revenue generation. Furthermore, key players are entering into exclusive partnerships and collaborations to increase the commercialization of innovative models for extensive use in research. For instance, in March 2022, Hera BioLabs announced an agreement with Charles River International Inc. for breeding and delivering its innovative SRG rat. This global license helps Hera BioLabs to commercialize its highly immunodeficient rats to a broader customer base.

Regional Insights

North America held the largest revenue share of over 45.0% in 2021. The growing prevalence of chronic conditions, the advent of novel infectious strains, and the rising healthcare economic burden in North America are likely to assist the research activities within the region. Growth in the number of research activities conducted by research and academic institutes is expected to fuel regional growth. For example, Simons Foundation Autism Research Initiative is collaborating with the Medical College of Wisconsin to generate and deliver engineered rat models of autism. This collaboration will cascade research activities for understanding autism in the future.

The APAC region is likely to be driven due to low research and labor costs. This probability of research at a lower cost in APAC countries such as Japan and India is anticipated to stimulate industry growth in this region. The Chinese market held a considerable share in 2021 and is anticipated to retain its dominance over the forecast period due to growing government spending on the overall research and development of pharmaceuticals and a significant rise in the number of clinical trials using animal models.

Key Players

genOway, Charles River Laboratories International, Inc., Envigo, Covance Inc., Horizon Discovery Group plc, Janvier Labs, Taconic Biosciences, Inc., and Biomedical Research Models (Biomere). 

Market Segmentation

• Type Outlook

  • Knockout

  • Outbred

  • Inbred

  • Hybrid

  • Immunodeficient

  • Conditioned

• Technology Outlook

  • Nuclear transferase

  • Microinjection

  • Embryonic stem cell

  • Other

• Service Outlook 

  • Cryopreservation

  • Breeding

  • Rederivation

  • Genetic testing

  • Quarantine depending

  • Other

• Application Outlook 

  • Oncology

  • Neurology

  • Immunology

  • Toxicology

  • Other

• End-use Outlook 

  • CROs

  • Academic and research facility

  • Healthcare companies

• Regional Outlook

  • North America

    • The U.S.

    • Canada

  • Europe

    • The U.K.

    • Germany

  • Asia Pacific

    • Japan

    • China

  • Latin America

    • Brazil

    • Mexico

  • Middle East and Africa (MEA)

    • South Africa

The Rat Model market research report covers definition, classification, product classification, product application, development trend, product technology, competitive landscape, industrial chain structure, industry overview, national policy and planning analysis of the industry, the latest dynamic analysis, etc., and also includes major. The study includes drivers and restraints of the global market. It covers the impact of these drivers and restraints on the demand during the forecast period. The report also highlights opportunities in the market at the global level.

The report provides size (in terms of volume and value) of Rat Model market for the base year 2020 and the forecast between 2021 and 2030. Market numbers have been estimated based on form and application. Market size and forecast for each application segment have been provided for the global and regional market.

This report focuses on the global Rat Model market status, future forecast, growth opportunity, key market and key players. The study objectives are to present the Rat Model market development in United States, Europe and China.

It is pertinent to consider that in a volatile global economy, we haven’t just conducted Rat Model market forecasts in terms of CAGR, but also studied the market based on key parameters, including Year-on-Year (Y-o-Y) growth, to comprehend the certainty of the market and to find and present the lucrative opportunities in market.

In terms of production side, this report researches the Rat Model capacity, production, value, ex-factory price, growth rate, market share for major manufacturers, regions (or countries) and type.

In terms of consumption side, this report focuses on the consumption of Rat Model by regions (countries) and application.

Buyers of the report will have access to verified market figures, including global market size in terms of revenue and volume. As part of production analysis, the authors of the report have provided reliable estimations and calculations for global revenue and volume by Type segment of the global Rat Model market. These figures have been provided in terms of both revenue and volume for the period 2017 to 2030. Additionally, the report provides accurate figures for production by region in terms of revenue as well as volume for the same period. The report also includes production capacity statistics for the same period.

With regard to production bases and technologies, the research in this report covers the production time, base distribution, technical parameters, research and development trends, technology sources, and sources of raw materials of major Rat Model market companies.

Regarding the analysis of the industry chain, the research of this report covers the raw materials and equipment of Rat Model market upstream, downstream customers, marketing channels, industry development trends and investment strategy recommendations. The more specific analysis also includes the main application areas of market and consumption, major regions and Consumption, major Chinese producers, distributors, raw material suppliers, equipment providers and their contact information, industry chain relationship analysis.

The research in this report also includes product parameters, production process, cost structure, and data information classified by region, technology and application. Finally, the paper model new project SWOT analysis and investment feasibility study of the case model.

Overall, this is an in-depth research report specifically for the Rat Model industry. The research center uses an objective and fair way to conduct an in-depth analysis of the development trend of the industry, providing support and evidence for customer competition analysis, development planning, and investment decision-making. In the course of operation, the project has received support and assistance from technicians and marketing personnel in various links of the industry chain.

The Rat Model market competitive landscape provides details by competitor. Details included are company overview, company financials, revenue generated, market potential, investment in research and development, new market initiatives, global presence, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width and breadth, application dominance. The above data points provided are only related to the companies’ focus related to Rat Model market.

Prominent players in the market are predicted to face tough competition from the new entrants. However, some of the key players are targeting to acquire the startup companies in order to maintain their dominance in the global market. For a detailed analysis of key companies, their strengths, weaknesses, threats, and opportunities are measured in the report by using industry-standard tools such as the SWOT analysis. Regional coverage of key companies is covered in the report to measure their dominance. Key manufacturers of Rat Model market are focusing on introducing new products to meet the needs of the patrons. The feasibility of new products is also measured by using industry-standard tools.

Key companies are increasing their investments in research and development activities for the discovery of new products. There has also been a rise in the government funding for the introduction of new Rat Model market. These factors have benefited the growth of the global market for Rat Model. Going forward, key companies are predicted to benefit from the new product launches and the adoption of technological advancements. Technical advancements have benefited many industries and the global industry is not an exception.

New product launches and the expansion of already existing business are predicted to benefit the key players in maintaining their dominance in the global market for Rat Model. The global market is segmented on the basis of region, application, en-users and product type. Based on region, the market is divided into North America, Europe, Asia-Pacific, Latin America and Middle East and Africa (MEA).

In this study, the years considered to estimate the market size of Rat Model are as follows:

• Historic Year: 2017-2020
• Base Year: 2021
• Forecast Year 2021 to 2030

Reasons to Purchase this Report:

- Market segmentation analysis including qualitative and quantitative research incorporating the impact of economic and policy aspects
- Regional and country level analysis integrating the demand and supply forces that are influencing the growth of the market.
- Market value USD Million and volume Units Million data for each segment and sub-segment
- Competitive landscape involving the market share of major players, along with the new projects and strategies adopted by players in the past five years
- Comprehensive company profiles covering the product offerings, key financial information, recent developments, SWOT analysis, and strategies employed by the major market players

Research Methodology:

In-depth interviews and discussions were conducted with several key market participants and opinion leaders to compile the research report.

This research study involved the extensive usage of both primary and secondary data sources. The research process involved the study of various factors affecting the industry, including the government policy, market environment, competitive landscape, historical data, present trends in the market, technological innovation, upcoming technologies and the technical progress in related industry, and market risks, opportunities, market barriers and challenges. The following illustrative figure shows the market research methodology applied in this report.

Market Size Estimation

Top-down and bottom-up approaches are used to estimate and validate the global market size for company, regional division, product type and application (end users).

The market estimations in this report are based on the selling price (excluding any discounts provided by the manufacturer, distributor, wholesaler or traders). Market share analysis, assigned to each of the segments and regions are achieved through product utilization rate and average selling price.

Major manufacturers & their revenues, percentage splits, market shares, growth rates and breakdowns of the product markets are determined through secondary sources and verified through the primary sources.

All possible factors that influence the markets included in this research study have been accounted for, viewed in extensive detail, verified through primary research, and analyzed to get the final quantitative and qualitative data. The market size for top-level markets and sub-segments is normalized, and the effect of inflation, economic downturns, and regulatory & policy changes or others factors are accounted for in the market forecast. This data is combined and added with detailed inputs and analysis from Vision Research Reports and presented in this report.

Market Breakdown and Data Triangulation

After complete market engineering with calculations for market statistics; market size estimations; market forecasting; market breakdown; and data triangulation. Extensive primary research was conducted to gather information and verify and validate the critical numbers arrived at. In the complete market engineering process, both top-down and bottom-up approaches were extensively used, along with several data triangulation methods, to perform market estimation and market forecasting for the overall market segments and sub-segments listed in this report.

Secondary Sources

Secondary Sources occupies approximately 25% of data sources, such as press releases, annual reports, Non-Profit organizations, industry associations, governmental agencies and customs data, and so on. This research study includes secondary sources; directories; databases such as Bloomberg Business, Wind Info, Hoovers, Factiva (Dow Jones & Company), TRADING ECONOMICS, and avention; Investing News Network; statista; Federal Reserve Economic Data; annual reports; investor presentations; and SEC filings of companies.

Primary Sources

 In the primary research process, various sources from both the supply and demand sides were interviewed to obtain qualitative and quantitative information for this report. The primary sources from the supply side include product manufacturers (and their competitors), opinion leaders, industry experts, research institutions, distributors, dealer and traders, as well as the raw materials suppliers and producers, etc.

The primary sources from the demand side include industry experts such as business leaders, marketing and sales directors, technology and innovation directors, supply chain executive, end users (product buyers), and related key executives from various key companies and organizations operating in the global market.

The study objectives of this report are:

• To analyze and study the global market capacity, production, value, consumption, status (2017-2020) and forecast (2021-2030);
• Focuses on the key manufacturers, to study the capacity, production, value, market share and development plans in future.
• Comprehensive company profiles covering the product offerings, key financial information, recent developments, SWOT analysis, and strategies employed by the major market players
• To define, describe and forecast the market by type, application and region.
• To analyze the global and key regions market potential and advantage, opportunity and challenge, restraints and risks.
• To identify significant trends and factors driving or inhibiting the market growth.
• To analyze the opportunities in the market for stakeholders by identifying the high growth segments.
• To strategically analyze each submarket with respect to individual growth trend and their contribution to the market
• To analyze competitive developments such as expansions, agreements, new product launches, and acquisitions in the market

To strategically profile the key players and comprehensively analyze their growth strategies.