Cancer Gene Therapy Market (By Therapy: Oncolytic Virotherapy, Gene Induced Immunotherapy, Gene Transfer; By End-user: Research institutes, Biopharma companies) - Global Industry Analysis, Size, Share, Growth, Trends, Revenue, Regional Outlook and Forecast 2022-2030

Cancer gene therapy has gained popularity in the last few years due to its high success rates during clinical and preclinical trials. The emerging field delivers a number of potential applications for cancer treatments. It offers various advances in the field of molecular biology, molecular genetics, immunology, virology, and molecular genetics. In various instances, this technique for cancer has been intended to augment existing therapies, such as immunotherapies and chemotherapies.

The cancer gene therapy approaches include oncolytic virotherapy, immunotherapy, and gene transfer. It can be utilized in different ways. For instance, altering gene regulation, replacing defective and missing genes with healthy genes, and introducing foreign genes into cells to change their function. The most common method is to replace a cancer-causing mutant gene with a healthy one.

Viral and non-viral vector products are needed for this technique. Non-viral vectors are normally utilized to transfer the different types of nucleic acids such as large DNA molecules ((Plasmid DNA: p DNA), small DNA, and RNA (m RNA, Si RNA, Ribozymes). Moreover, viral-vector therapies use modified viruses as drug-delivery vehicles to insert specific DNA sequences- regulatory RNAs (e.g. siRNAs), encoding genes, or other therapeutic substrates into cells.

Despite the slow clinical progress, researchers are undertaking efforts to develop specific non-toxic cancer therapies that are rising exponentially. As of now, more than 500 products under trial have been listed with the FDA. There is a number of strategies currently being followed during the cancer treatments. For instance,

  • Minimize cancerous cell proliferation and rise cell cycle control by restoring functions such as RB and p53
  • Rise in immunological rejection of tumor by the host

The pipeline for cancer therapies is quite strong and various companies are engaged in developing efficient products. Small biopharma companies are also emerging in the cell and gene therapy industry. For instance, Autolus Therapeutics is developing AAV-based gene therapies. The company is targeting patients suffering from chronic, systemic diseases using this technique.

Moreover, improving the regulatory scenario is also expected to increase the product launch in the market. For instance, in March 2021, Bluebird Bio and Bristol Myers Squibb received FDA approval for Abecma (idecabtagene vicleucel). It is a cell-based gene therapy to treat patients with multiple myeloma.

In addition, in February 2022, the University of Pennsylvania doctors’ team announced that cancer patients treated with gene therapy in 2010 shows no sign of cancer in the body. The two examples demonstrate how the therapy, known as CAR-T cell therapy, can fight cancer right away inside the body, and evolve to battle against the tumor. Moreover, in July 2022, ImmunoACT, backed by Laurus Labs, announced that it tested a novel gene therapy cure for leukemia and lymphoma. The lab is working with CD19 CAR-T Cell for leukemia and lymphoma. According to the lab, findings begin to appear after about a week.

Key Players

  • Abeona Therapeutics
  • Asklepios BioPharmaceutical
  • Celgene
  • Elevate Bio
  • GlaxoSmithKline
  • Bluebird bio
  • Genelux Corporation
  • OncoGenex Pharmaceuticals
  • Introgen Therapeutics
  • Altor Bioscience
  • Merck
  • GenVec
  • BioCancell

Market Segmentation

  • By Therapy
    • Oncolytic Virotherapy
    • Gene-induced Immunotherapy
    • Gene Transfer
  • By End-user
    • Research Institutes
    • Biopharma Companies
    • Diagnostic Centres
    • Others
  • By Region
    • North America
    • Europe
    • Asia Pacific
    • Latin America
    • Middle East & Africa

Chapter 1. Introduction

1.1. Research Objective

1.2. Scope of the Study

1.3. Definition

Chapter 2. Research Methodology

2.1. Research Approach

2.2. Data Sources

2.3. Assumptions & Limitations

Chapter 3. Executive Summary

3.1. Market Snapshot

Chapter 4. Market Variables and Scope 

4.1. Introduction

4.2. Market Classification and Scope

4.3. Industry Value Chain Analysis

4.3.1. Raw Material Procurement Analysis 

4.3.2. Sales and Distribution Channel Analysis

4.3.3. Downstream Buyer Analysis

Chapter 5. COVID 19 Impact on Cancer Gene Therapy Market 

5.1. COVID-19 Landscape: Cancer Gene Therapy Industry Impact

5.2. COVID 19 - Impact Assessment for the Industry

5.3. COVID 19 Impact: Global Major Government Policy

5.4. Market Trends and Opportunities in the COVID-19 Landscape

Chapter 6. Market Dynamics Analysis and Trends

6.1. Market Dynamics

6.1.1. Market Drivers

6.1.2. Market Restraints

6.1.3. Market Opportunities

6.2. Porter’s Five Forces Analysis

6.2.1. Bargaining power of suppliers

6.2.2. Bargaining power of buyers

6.2.3. Threat of substitute

6.2.4. Threat of new entrants

6.2.5. Degree of competition

Chapter 7. Competitive Landscape

7.1.1. Company Market Share/Positioning Analysis

7.1.2. Key Strategies Adopted by Players

7.1.3. Vendor Landscape

7.1.3.1. List of Suppliers

7.1.3.2. List of Buyers

Chapter 8. Global Cancer Gene Therapy Market, By Therapy

8.1. Cancer Gene Therapy Market, by Therapy, 2022-2030

8.1.1. Oncolytic Virotherapy

8.1.1.1. Market Revenue and Forecast (2017-2030)

8.1.2. Gene-induced Immunotherapy

8.1.2.1. Market Revenue and Forecast (2017-2030)

8.1.3. Gene Transfer

8.1.3.1. Market Revenue and Forecast (2017-2030)

Chapter 9. Global Cancer Gene Therapy Market, By End-user

9.1. Cancer Gene Therapy Market, by End-user, 2022-2030

9.1.1. Research Institutes

9.1.1.1. Market Revenue and Forecast (2017-2030)

9.1.2. Biopharma Companies

9.1.2.1. Market Revenue and Forecast (2017-2030)

9.1.3. Diagnostic Centres

9.1.3.1. Market Revenue and Forecast (2017-2030)

9.1.4. Others

9.1.4.1. Market Revenue and Forecast (2017-2030)

Chapter 10. Global Cancer Gene Therapy Market, Regional Estimates and Trend Forecast

10.1. North America

10.1.1. Market Revenue and Forecast, by Therapy (2017-2030)

10.1.2. Market Revenue and Forecast, by End-user (2017-2030)

10.1.3. U.S.

10.1.3.1. Market Revenue and Forecast, by Therapy (2017-2030)

10.1.3.2. Market Revenue and Forecast, by End-user (2017-2030)

10.1.4. Rest of North America

10.1.4.1. Market Revenue and Forecast, by Therapy (2017-2030)

10.1.4.2. Market Revenue and Forecast, by End-user (2017-2030)

10.2. Europe

10.2.1. Market Revenue and Forecast, by Therapy (2017-2030)

10.2.2. Market Revenue and Forecast, by End-user (2017-2030)

10.2.3. UK

10.2.3.1. Market Revenue and Forecast, by Therapy (2017-2030)

10.2.3.2. Market Revenue and Forecast, by End-user (2017-2030)

10.2.4. Germany

10.2.4.1. Market Revenue and Forecast, by Therapy (2017-2030)

10.2.4.2. Market Revenue and Forecast, by End-user (2017-2030)

10.2.5. France

10.2.5.1. Market Revenue and Forecast, by Therapy (2017-2030)

10.2.5.2. Market Revenue and Forecast, by End-user (2017-2030)

10.2.6. Rest of Europe

10.2.6.1. Market Revenue and Forecast, by Therapy (2017-2030)

10.2.6.2. Market Revenue and Forecast, by End-user (2017-2030)

10.3. APAC

10.3.1. Market Revenue and Forecast, by Therapy (2017-2030)

10.3.2. Market Revenue and Forecast, by End-user (2017-2030)

10.3.3. India

10.3.3.1. Market Revenue and Forecast, by Therapy (2017-2030)

10.3.3.2. Market Revenue and Forecast, by End-user (2017-2030)

10.3.4. China

10.3.4.1. Market Revenue and Forecast, by Therapy (2017-2030)

10.3.4.2. Market Revenue and Forecast, by End-user (2017-2030)

10.3.5. Japan

10.3.5.1. Market Revenue and Forecast, by Therapy (2017-2030)

10.3.5.2. Market Revenue and Forecast, by End-user (2017-2030)

10.3.6. Rest of APAC

10.3.6.1. Market Revenue and Forecast, by Therapy (2017-2030)

10.3.6.2. Market Revenue and Forecast, by End-user (2017-2030)

10.4. MEA

10.4.1. Market Revenue and Forecast, by Therapy (2017-2030)

10.4.2. Market Revenue and Forecast, by End-user (2017-2030)

10.4.3. GCC

10.4.3.1. Market Revenue and Forecast, by Therapy (2017-2030)

10.4.3.2. Market Revenue and Forecast, by End-user (2017-2030)

10.4.4. North Africa

10.4.4.1. Market Revenue and Forecast, by Therapy (2017-2030)

10.4.4.2. Market Revenue and Forecast, by End-user (2017-2030)

10.4.5. South Africa

10.4.5.1. Market Revenue and Forecast, by Therapy (2017-2030)

10.4.5.2. Market Revenue and Forecast, by End-user (2017-2030)

10.4.6. Rest of MEA

10.4.6.1. Market Revenue and Forecast, by Therapy (2017-2030)

10.4.6.2. Market Revenue and Forecast, by End-user (2017-2030)

10.5. Latin America

10.5.1. Market Revenue and Forecast, by Therapy (2017-2030)

10.5.2. Market Revenue and Forecast, by End-user (2017-2030)

10.5.3. Brazil

10.5.3.1. Market Revenue and Forecast, by Therapy (2017-2030)

10.5.3.2. Market Revenue and Forecast, by End-user (2017-2030)

10.5.4. Rest of LATAM

10.5.4.1. Market Revenue and Forecast, by Therapy (2017-2030)

10.5.4.2. Market Revenue and Forecast, by End-user (2017-2030)

Chapter 11. Company Profiles

11.1. Abeona Therapeutics

11.1.1. Company Overview

11.1.2. Product Offerings

11.1.3. Financial Performance

11.1.4. Recent Initiatives

11.2. Asklepios BioPharmaceutical

11.2.1. Company Overview

11.2.2. Product Offerings

11.2.3. Financial Performance

11.2.4. Recent Initiatives

11.3. Celgene

11.3.1. Company Overview

11.3.2. Product Offerings

11.3.3. Financial Performance

11.3.4. Recent Initiatives

11.4. Elevate Bio

11.4.1. Company Overview

11.4.2. Product Offerings

11.4.3. Financial Performance

11.4.4. LTE Scientific

11.5. GlaxoSmithKline

11.5.1. Company Overview

11.5.2. Product Offerings

11.5.3. Financial Performance

11.5.4. Recent Initiatives

11.6. Bluebird bio

11.6.1. Company Overview

11.6.2. Product Offerings

11.6.3. Financial Performance

11.6.4. Recent Initiatives

11.7. Genelux Corporation

11.7.1. Company Overview

11.7.2. Product Offerings

11.7.3. Financial Performance

11.7.4. Recent Initiatives

11.8. OncoGenex Pharmaceuticals

11.8.1. Company Overview

11.8.2. Product Offerings

11.8.3. Financial Performance

11.8.4. Recent Initiatives

11.9. Introgen Therapeutics

11.9.1. Company Overview

11.9.2. Product Offerings

11.9.3. Financial Performance

11.9.4. Recent Initiatives

11.10. Altor Bioscience

11.10.1. Company Overview

11.10.2. Product Offerings

11.10.3. Financial Performance

11.10.4. Recent Initiatives

Chapter 12. Research Methodology

12.1. Primary Research

12.2. Secondary Research

12.3. Assumptions

Chapter 13. Appendix

13.1. About Us

13.2. Glossary of Terms

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