U.S. Cell Culture Market (By Product; By Application: Biopharmaceutical Production, Drug Development, Diagnostics, Tissue Culture & Engineering) - Industry Analysis, Size, Share, Growth, Trends, Revenue, Regional Outlook and Forecast 2024-2033

U.S. Cell Culture Market Size and Trends

The U.S. cell culture market size was estimated at around USD 5.64 billion in 2023 and it is projected to hit around USD 14.7 billion by 2033, growing at a CAGR of 10.05% from 2024 to 2033.

Key Pointers

• By Product, the consumables segment held the largest revenue share of 59% in 2023.
• By Product, the instruments segment is expected to witness significant growth at a promising CAGR from 2024 to 2033.
• By Application, the biopharmaceutical production segment generated the maximum market share of 32% in 2023.
• By Application, the diagnostics segment is expected to expand at the highest CAGR from 2024 to 2033.

U.S. Cell Culture Market Overview

The United States cell culture market is experiencing a notable surge in growth, driven by advancements in biotechnology, pharmaceuticals, and research sectors. Cell culture, a vital technique in modern biological research, involves the cultivation of cells outside their natural environment under controlled conditions

U.S. Cell Culture Market Growth Factors

The growth of the U.S. cell culture market is propelled by the continuous technological advancements, such as the development of 3D cell culture techniques and automation, are enhancing efficiency and scalability in cell-based research and manufacturing processes. Secondly, increased investments in research and development across pharmaceutical, biotechnology, and academic sectors are driving demand for cell culture products and services. Thirdly, the growing biopharmaceutical industry, characterized by the rising demand for monoclonal antibodies, vaccines, and cell therapies, is fueling adoption of cell culture technologies for large-scale production.

U.S. Cell Culture Market Trends:

• Increased R&D Investments: Rising investments in research and development by pharmaceutical, biotechnology, and academic institutions are driving demand for cell culture products and services.
• Growing Biopharmaceutical Industry: The increasing demand for biopharmaceuticals, including monoclonal antibodies, vaccines, and cell therapies, is spurring adoption of cell culture technologies for large-scale production.
• Emerging Applications: Novel applications such as personalized medicine, organ-on-a-chip technology, and stem cell therapy are expanding the utility of cell culture in biomedical research and therapeutic development.

U.S. Cell Culture Market Restraints:

• Ethical Considerations: Ethical concerns related to the use of animal-derived cell culture components and human cell lines, as well as issues surrounding informed consent and genetic privacy, present ethical dilemmas and may impact market growth.
• Complexity of Reproducing Physiological Conditions: Despite advancements, replicating the complex physiological microenvironment in vitro remains challenging, limiting the relevance and translational potential of cell culture models for certain applications, such as drug efficacy and toxicity testing.
• High Cost of Technology Adoption: The initial capital investment required for implementing advanced cell culture technologies, including equipment, infrastructure, and skilled personnel, can be prohibitive for some stakeholders, particularly smaller research institutions and laboratories.
• Limited Standardization and Reproducibility: Variability in cell culture protocols, media formulations, and cell lines across different laboratories can result in inconsistencies and irreproducibility of experimental results, posing challenges for data interpretation and validation.

Product Insights

The market comprises two main segments: consumables and instruments. Consumables accounted for the largest revenue share, holding 59% in 2023. This dominance is attributed to the consistent demand for consumables and the ongoing R&D investments by biotechnology and biopharmaceutical companies, particularly in the development of advanced biologics like monoclonal antibodies and vaccines. The demand for consumables is projected to remain robust throughout the forecast period, with reagents, media, and sera being the primary subcategories. Among these, media holds the largest market share within the consumables segment.

On the other hand, the instruments segment is expected to witness significant growth at a promising CAGR during the forecast period. These instruments find applications in diverse areas such as vaccination, cancer research, drug screening and development, recombinant products, toxicity testing, stem cell technology, regenerative therapies, and other sectors served by end-users including industrial, biotechnology, and agriculture. Notably, FUJIFILM Corporation made a substantial investment of USD 1.6 billion in June 2022 to expand and enhance its cell culture manufacturing services, signaling further potential for growth in this segment. This investment is poised to bolster FUJIFILM's facilities in Denmark and Texas, underlining the company's commitment to meeting the evolving needs of the market.

Application Insights

The market is divided by application into several segments, including biopharmaceutical production, drug development, diagnostics, tissue culture and engineering, cell and gene therapy, toxicity testing, and other applications. In 2023, the biopharmaceutical production segment dominated the market with a 32% revenue share and is projected to experience the fastest growth rate throughout the forecast period. Mammalian cell cultures are predominantly utilized in biopharmaceutical production, driven by the escalating demand for genetically enhanced drugs and unconventional therapeutic options. Consequently, there's a surge in the demand for various cell culture consumables, particularly media.

The diagnostics segment is poised for significant growth with a notable CAGR over the forecast period. Cell cultures find application in metabolomics for identifying biomarkers associated with pathological conditions. Moreover, they enable the identification of metabolic pathways leading to the production of such biomarkers, aiding in the diagnosis of underlying metabolic disorders. Additionally, metabolites play a pivotal role in cancer diagnosis and recurrence detection, expanding the application spectrum for cell culture products and driving market growth.

U.S. Cell Culture Market Key Companies

• Sartorius AG
• Danaher
• Merck KGaA
• Thermo Fisher Scientific, Inc.
• Corning Inc.
• Avantor, Inc.
• BD
• Eppendorf SE
• Bio-Techne
• PromoCell GmbH

Recent Developments

• In March 2023, Danaher and the University of Pennsylvania unveiled a strategic alliance aimed at advancing cell therapy. This multi-year partnership focuses on developing new technologies, streamlining manufacturing processes, and delivering next-generation engineered cell products to patients, with the goal of achieving more consistent clinical outcomes.
• In February 2023, Thermo Fisher Scientific and Celltrio announced a collaborative effort to offer clients in the biotherapeutics industry a fully integrated cell culture system, providing precise control over the culture environment.
• In the same month, Corning Incorporated showcased its latest advancements in automation and 3D cell culture technology at the Society for Laboratory Automation & Screening (SLAS) conference in San Diego, California.

U.S. Cell Culture Market Segmentation:

By Product

• Consumables
  • Sera
    • Fetal Bovine Serum
    • Other
  • Reagents
    • Albumin
    • Others
  • Media
    • Serum-free Media
      • CHO Media
      • HEK 293 Media
      • BHK Medium
      • Vero Medium
      • Other Serum-free Media
      • Classical Media
      • Stem Cell Culture Media
      • Chemically Defined Media
      • Specialty Media
      • Other Cell Culture Media
• Instruments
  • Culture Systems
  • Incubators
  • Centrifuges
  • Cryostorage Equipment
  • Pipetting

By Application

• Biopharmaceutical Production
  • Monoclonal Antibodies
  • Vaccines Production
  • Other Therapeutic Proteins
• Drug Development
• Diagnostics
• Tissue Culture & Engineering
• Cell & Gene Therapy
• Toxicity Testing
• Other Applications